Randomized controlled trials (RCT) remain the gold standard for evaluating the safety and efficacy of drugs before making them available to patients. However, drug development is increasingly shifting towards specialty medications with narrow indications and smaller patient populations. Under these conditions, clinical trials may not be able to recruit enough patients and can take too long to complete.
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Rethinking the Use of Real-World Evidence to Improve Policy Decisions
Randomized controlled trials (RCT) remain the gold standard for evaluating the safety and efficacy of drugs before making them available to patients. However, drug development is increasingly shifting towards specialty medications with narrow indications and smaller patient populations. Under these conditions, clinical trials may not be able to recruit enough patients and can take too long to complete.
By American Journal of Managed Care April 19, 2019
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